THE RELATIONSHIP BETWEEN RISK FACTORS AND SEVERITY LEVEL OF ACQUIRED WEAKNESS ICU EVENTS IN CRITICAL PATIENTS AT DR. SOETOMO HOSPITAL

Abstract

Objectives: ICU advancements enhance critical patient survival but also raise ICU-Acquired Weakness (ICU-AW) cases due to limb weakness. ICU-AW, occurring in 47-70% of patients, lacks effective treatment, emphasizing the significance of prevention amid risk factors and patient severity considerations. Hence, this study aimed to analyze the relationship between risk factors and the severity of the incidence of ICU-AW in critical patients in the Intensive Care Unit of Dr. Soetomo Hospital, Surabaya.

Methods: This research was a cross-sectional study with 30 participants conducted in the Intensive Care Unit of Dr. Soetomo Hospital, Surabaya. SPSS was used for statistical analysis.

Results: Sepsis and SOFA Score had a significant relationship with the incidence of ICU-AW (p<0.05), while corticosteroid use, hyperglycemia, duration of NMBA use and sedation, and APACHE II Score did not have a significant relationship (p>0.05). The influence of risk factors and severity on the incidence of ICU-AW had an R2 value of 0.349, with the largest Exp(β) being sepsis. Delta (Δ) SOFA Score on day 1 and SOFA Score on day 3 had a simultaneous effect on the Nagelkerke R Square value of 0.1 and sig.0.205. SOFA Score on day 1 had an effect of 16.8%, while APACHE Score on day 1 was 1.6%.

Conclusion: In terms of risk factors and severity, sepsis and SOFA Score have a significant relationship with the incidence of ICU-Acquired Weakness.