ACUTE MYOCARDIAL INFARCTION - CLINICAL PROFILE OF 1000 CASES

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ABDUL HAMEED SIDDIUQI, AZHAR MEHMOOD KAYANI

Abstract

Acute myocardial infarction is the most common and potentially life-threatening cardiac emergency
presenting to a hospital. Having significant mortality and morbidity, the emergency requires early
recognition, efficient triage and prompt therapeutic, interventions for maximum benefit. We report clinical
profile and management pattern of 1000 cases of myocardial infarction admitted at our institute. In our
study, male/female ratio was 8:1. 21.4% were diabetics, 29.1% were hypertensives, 49.2% were current
smokers and 9.1% cases had a family history of premature CAD. At the institute, 97.7% patients were given
aspirin, 51.6% received SK, ACE inhibitors were given to 72.9% and beta blockers were administered in.
61.8% of patients Calcium antagonists were given to 16% patients, mostly due to some contra-indication to
beta blockers. 5.2% had some form of bradyarrhythamia while 8% grade of ventricular arrhythmia. 13.2%
patients died in hospital. Of these, 42% died of pump failure, 34% died due to cardiac arrest, 8% died due to
refractory arrhythmias and rest due to miscellaneous causes. Mean hospital stay was 5.7 days. Overall inhospital
mortality was 13. 2%. General pattern of management and mortality compares with or is better than
international reported figures and reflects high standard of professional care at the institute.

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