HEART MUSCLE DISEASES THE CARDIOMYOPATHIES 116 MYOCARDIUM IN DIABETES

Abstract

Conclusions:

On the basis of available morphologic data in human and experirnental diabetic animals, it is concluded that chronic diabetes mellitus can alter myocardial composition and functjn independent .of vascular defects. The relative prominence of glycoprotein in the myccardial interstitjum of both human and experimental animals suggests a basis fc• the diminished diastolic compliance in the diabetic heart.  Treatment of hypertension and hyperlipidemia are as important as in the none—diabetic population. It remains an open question whether an individual with mild hyperglycemia may benefit from low dose insulin to strictly control blood glucose levels.

Acknowledgement:

We appreciate the technical assistance provided by many of our colleagues, cardiac fellows, RNs and technicians in the cardiac cath room and support laboratories. We thank Mrs. Charlotte Blocker for typing the manuscript.