A Comprehensive Review on Recent Progress in Invivo and Invitro Models for Hyperlipidemia Studies

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Anubhav Dubey, Sribatsa Lanchhana Dash, Mamta Kumari, Shweta Patel, Shweta Singh, Suruchi Agarwal

Abstract

Hyperlipidemia refers to an abnormality in plasma lipid levels. Research conducted in India indicates that the prevalence of elevated cholesterol is greatest in the country's metropolitan areas. Lifestyle factors, inactivity, and a diet heavy in saturated fat are at the root of most cases of hyperlipidemia. It's classified in two ways. Hypercholesterolemia and hypertriglyceridemia, as well as hereditary and acquired forms, may be distinguished. Modifying one's diet and way of life is often sufficient to cure hyperlipidemia. If they're too high, medication (allopathic or ayurvedic) will be required. Statins and fibrates are the two medications that get the most use. Plasma lipids may be boosted by inducing agents. Triton X100, Triton WR 1339, and Methionine are three of the most common inducing agents used in in vitro and in vivo studies. Hyperlipidemia may be treated with a change in diet; therefore, effective natural home treatments are available.

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