Phytochemical Screening and Combined Invitro Anti-Microbial and Anti-Oxidant Studies of Various Extracts of Vinca Ixora Coccinea

Abstract

Ixora coccinea belonging to family Rubiaceous an evergreen shrub presents in many regions of India and throughout the world. It contains various therapeutic properties such as antitumour, wound healing, antioxidant activity, gastroprotective, hepatoprotective, antidiarrheal, antinociceptive, antimutagenic, antineoplastic and chemo preventive effects. Phytochemical investigation shows the presence of flavonoid, saponin, tannin, alkaloid, glycoside, phenol. Antioxidant is a chemical substance that prevents oxidation of other chemical substances by neutralising damaging effect of free radicals. Antioxidants are mainly present in phenolic compounds. Phenolic compounds show antioxidant capacity due to redox properties they act as a reducing agent, hydrogen donors, metal chelators singlet oxygen quenchers. Free radical is an atom or molecule processing unpaired electrons. The ROS oxygen derived free radicals such as superoxide anion[O2], Hydroxyl [OH], Hydroperoxyl [OOH], Peroxyl [ROO] and hypochlorous acid [HOCL].