Evaluation of Geranium wallichianum D. Don Ex Sweet's Ethanolic Extract's Anti-Ulcer Activity

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Tapsya Sharma, Vir Vikram, Saurabh Sharma


The current investigation gives proof that the ulcer-fighting properties of Geranium wallichianum D. Don Ex Sweet exist. The plant generated a large amount of antiulcer activity, which was marked by anti-secretory, cytoprotective, and proton pump inhibitory qualities. More investigation is needed to determine the chemical element of this extract that gives rise to its antiulcer activity. One of the most common conditions that affect the digestive tract is the peptic ulcer. Although the precise causes of peptic ulcer illness are not entirely understood, experts think that an imbalance in the secretion of the digestive acids, pepsin, and acid, as well as a lack of protective mechanisms in the mucosa, may contribute to the disease. Nonsteroidal anti-inflammatory drug use, H. pylori infection, stress, or pathological conditions like Zollinger-Ellison Syndrome are the most frequent causes of peptic ulcer disease. The family Geraniaceae includes the plant species Geranium wallichianum D. Don ex Sweet. It has numerous potential applications in medicine. It is commonly found on the Himalayan mountain sides, in Assam, and in Nepal. The rhizomes of Geranium wallichianum D. Don Ex Sweet have been found to contain volatile oil, gycozoline, xanthotoxin, and alkaloids, according to the results of a phytochemical investigation. Researchers have found that the leaf extract contains hepatoprotective, antibacterial, anti-dysentery, and anti-oxidant properties. It also has hypoglycemic and antibacterial properties. The leaf extract of this plant are loaded with these kinds of antiulcer capabilities.

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