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Pterocarpus. santalinus L. f., a plant of notable significance, is extensively employed in the treatment of several ailments owing to its abundant therapeutic attributes. Pterocarpus santalinus L. f. family fabaceae known as red sandalwood. It is a deciduous tree of small-to-medium size. In this study in vitro antioxidant, anti-inflammatory, and antimicrobial activity of P. santalinus L. f. leaves, heartwood extracts were investigated. P. santalinus L. f. leaves, heartwood both extracts showed impressive antioxidant activity and when compared to ibuprofen, heartwood extract showed the strongest anti-inflammatory effect. The results of this study also showed significant antimicrobial action against Helicobacter pylori (ATCC 43579), E. coli (ATCC 29181), Staphylococcus aureus (ATCC-6538), and Klebsiella pneumoniae (K36). The highest zone of inhibition was demonstrated by P. santalinus L. f. heartwood extract. Thus, it appears from the available data that P. santalinus L. f. has significant biopotential, and its application as a powerful medicinal agent deserves consideration.
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