The Impact Of Dietary Interventions On The Survival Of Patients With Chronic Kidney Disease: A Narrative View

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Ms. Arpitaben J. Parekh, Dr. Anita Prakasam

Abstract

Chronic Kidney Disease (CKD) poses a significant global health challenge, necessitating exploration into interventions that may impact disease trajectory. Dietary strategies have emerged as a crucial area of investigation due to their potential influence on CKD progression and patient outcomes. This systematic review examines the relationship between dietary interventions and survival in CKD patients by synthesizing evidence from 17 studies encompassing randomized controlled trials, cohort studies, and observational investigations. Promising dietary patterns, including plant-based, Mediterranean, and DASH diets, demonstrate associations with improved outcomes. Nutrient-specific considerations reveal mixed findings on the optimal protein intake, while moderate sodium restriction appears beneficial, especially in early CKD stages. Calorie restriction's impact on CKD survival remains uncertain. Higher fruit and vegetable intake, along with moderate fish consumption, are associated with lower mortality. Limitations include study heterogeneity, emphasizing the need for larger, long-term studies for definitive conclusions. The findings underscore the complexity of CKD dietary management, suggesting personalized approaches and the importance of further research for refining optimal nutrient intake levels across different CKD stages. Overall, dietary modifications show promise, offering valuable insights for clinicians, policymakers, and researchers navigating the intricate landscape of CKD management.


 


Keywords: Chronic Kidney Disease, diet, survival, systematic review, mortality, dietary interventions.

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