A prospective observational study for the assessment of left ventricular systolic function by comparing Simpon’s biplane method and global longitudinal strain method in pre and post operative percutaneous coronary intervention patients

Abstract

Background:

The Global Longitudinal Strain method is one of the sensitive markers to assess LVSF accurately when compared to Simpson biplane method. The reliability and precision of assessment of myocardial motion by Simpson biplane method and myocardial deformation differ from the volume-based measurements. For the measurement of myocardial function, the evaluation of GLS from speckle tracking analysis of 2D echocardiography has emerged as a therapeutically viable substitute for Simpson biplane method. The usefulness of GLS as a supplementary parameter to LVEF for integration into standard clinical practice is evaluated.

Methods:

A prospective observational study was done in 100 CAD patients who underwent PCI were included in this study after obtaining informed consent from each patient and ethical committee approval. Echocardiography was performed for the patients, and LVEF was measured by the Simpson’s and GL strain methods. Accurate LV systolic function is statistically analyzed by using Pearson’s correlation between pre- and post-PCI Simpson’s and GLS methods. A significant difference for Simpsons and GLS was considered.

Result:

A statistically significant association was found between Simpsons and GLS measurements. Pre PCI Simpsons & GLS is 5.04 x 10^-76 and post PCI Simpsons & GLS is 1.07 x 10^-76      i.e.,P value <0.05. Both the parameters were moderately correlated. GLS provides better predictivity than Simpsons biplane method.

Conclusion:

The study shows that GLS is more sensitive predictor to assess LVSF when compared to Simpson’s method in pre & post PCI patients.