Amiodarone Induced Proximal Myopathy

Abstract

Twentythree patients were put on amiodarone after M.I. for reasons like recurr ent tachycardia and frequent ventricular premature beats. Out of 23, eleven patients were diabetic. The duration of diabetes was 4.5+2 years. Patients were followed up for one year. Three out of eleven diabetics, developed proximal symmetrical myopathy. Nerve conduction studies were normal in 2 out of 3 affected patients. The average duration of diabetes was 5 years in affected individuals. The myopathy was reversible after withdrawal of drug.